R 379.00

120 Capsules120 Capsules
SKU: N/ACategories: Bestsellers, Home page, WEIGHT LOSS
Product Summary

Specially formulated weight loss supplement for sugar, insulin and leptin control. A combination of selected herbal extracts, a trace element and anti-oxidants for accelerated weight reduction.

Benefits and Indications:

  • Assists with sugar (glucose) control
  • Assists with insulin control
  • Assists with leptin control
  • Assist with energy production in mitochondria
  • Assists with liver detoxification, enhanced blood circulation, inflammation reduction and mitochondrial energy production
  • Contains powerfull antioxidants to neutralize free radicals

Daily dose of 6 capsules: Milk Thistle extract Dandelion extract Grapeseed extract Berberine extract N-Acetyle-L-Carnitine Chromium Polynicotinate Alpha Lipoic Acid 


Not to be used if sensitive or allergic to any of the ingredients, or if pregnant or breastfeeding

  • Contents per capsule 500mg
  • Milk Thistle extract - 200mg
  • Dandelion extract - 350mg
  • Grapeseed extract - 500mg
  • Berberine extract - 300mg
  • N-Acetyle-L-Carnitine - 500mg
  • Chromium Polynicotinate - 500mg

Dosage and Directions for use

Take 2 capsules with meals 2 - 3 times per day. Best taken with 200-300ml water


For any weight loss programme to be effective, it must include a sensible calorie restricted diet and exercise programme. It is advisable to consult a registered medical practitioner for a medical evaluation.

Storage Instructions

Store in a cool dry place below 25°C away from direct sunlight and moisture. Keep lid tightly closed.

Keep out of reach of children.


This food supplement has not been evaluated by the FDA or SAHPRA.  It is not intended to diagnose or treat any illness or disease.  If you are ill, consult a registered doctor or health care practitioner.

Product Overview


Excessive weight gain, obesity or diabetes may be associated with multiple causes and lifestyle factors such as, diet, genetic inheritance from a parent or parents, medical conditions, for example thyroid and hormonal disorders, chronic constipation, over eating, lack of exercise, psycho-emotional stress or medication, as well as dysbiosis (unhealthy gut bacteria).

Common Problems with Weight Loss Programs and Products:

Many Weight Loss Programs do not address the issue of blood glucose control, insulin resistance and leptin resistance which is one of the most important factors in the success or failure of a Weight Loss Program.  Many individuals adhere to a reduced calorie intake diet and frequent exercising and still cannot lose weight.  Under ideal circumstances it is best to have a medical check-up and have blood chemistry tests performed for blood glucose (HbA1C), insulin, thyroid, oestrogen (if female) and adrenal hormone levels.

Definition of Leptin:

Leptin is a hormone released from fat cells which signals the brain to control eating and the storage of fat for energy.

Definition of Leptin Resistance:

Leptin resistance involves a reduced ability of Leptin receptors in the fat cells to respond to the effects of Leptin.  This leads to increased (excessive) production of Leptin, which results in storage of fat in the body, instead of the fat being broken down for energy which happens in normal weight individuals.

Insulin Resistance:

Insulin Resistance is a condition which develops in your cells in your muscles, liver and fat when they no longer respond normally to insulin (insulin carries your sugar into your cells to be used for energy production).  This means that the body cannot get enough glucose for energy.  The pancreas (which secretes insulin) then has to produce more and more insulin to get the sugar into the cells.  This is called Insulin Resistance.  With time your blood sugar levels go higher and higher which leads to excess fat storage, weight gain, diabetes and damage to blood vessels, nerves, immune system and organs.

Blood Sugar Control:

Blood Sugar Control in the body is achieved by diet control (especially carbohydrates), leptin which controls appetite and fat storage and insulin, the hormone from the pancreas which controls the transport of sugar (mostly glucose) but also fats, into the cells to be used for energy.  Other factors and organs which play a role in controlling blood sugar are the liver, the adrenal glands, the thyroid, the muscles, your genetics, nutrients, stress, exercise, sleep, psycho-emotional factors, diseases, temperature and medication.

Reason for developing the product:

Research has shown that persons afflicted with excessive weight or obesity have blood levels of Leptin that are five times higher than those of normal, healthy persons (although Leptin exerts anti-obesity effects, persons afflicted with excess weight are insensitive to its effects) this phenomena is known as Leptin Insensitivity or Leptin Resistance.

Just like Insulin Resistance in diabetics and overweight persons, Leptin Resistance, can lead to weight gain and obesity.  There are quite a few products to assist with Insulin Resistance only, but very few if any which address the issue of Leptin Resistance or Insensitivity and no known products which address all three problems of Leptin Resistance, Insulin Resistance and Blood Sugar Control, hence the need to develop such a product.

Contents, Function and Benefits:

Milk Thistle extract:

Due to its Silymarin content, Milk Thistle assists with various functions in the liver, boosting Insulin sensitivity as well as Leptin sensitivity. It acts as an anti-oxidant and promotes the synthesis of endogenous proteins within the liver, while protecting the body against the harmful effect of various toxic and poisonous substances. The liver, being the biggest filter in our bodies, handles thousands of processes per minute.  An unhealthy liver can’t break down toxins, leading to a build-up of stored fat and toxins. In order to lose weight effectively, we have to address liver function first.

Dandelion extract:

Dandelion extract alleviates congestion in the liver, lowers blood sugar levels and increases the body’s sensitivity to Leptin. Dandelion also supports kidney health and assists the body to get rid of toxins.

Grapeseed extract:

The active ingredients in Grapeseed extract are known as proanthocyanidins which are well known anti-oxidants which assist with healing a fatty liver and enhancing the function of the liver to rid the body of toxins. It increases both Leptin and Insulin sensitivity.

Chromium polynicotinate 500mcg:

Chromium is a trace element found in very small quantities in the body, but essential for insulin activity.  Chromium Polynicotinate is a form of Chromium.  Chromium plays a role in the storage of carbohydrates, fats and protein.  It also plays a role in appetite control and Chromium Polynicotinate therefore indirectly can help to burn more calories, reduce body fat and enhance muscle mass, by assisting with insulin function.  Chromium (trivalent) can also help with depression, PCOS, lowers “bad” LDL Cholesterol and can raise “good” HDL Cholesterol.

Alpha Lipoic Acid:

Is a unique fat and water soluble anti-oxidant made naturally by the body but also found in various foods and supplements.  It has multiple roles and benefits, namely:  Can help balance sugar levels and reduce the risk and side effects of diabetes, reduce inflammation, improve nerve function, slow down skin ageing, neutralize free radicals, promote healthy mitochondrial energy production, increase weight loss, reduce insulin resistance, reduce memory loss and reduce risk of heart disease.

Berberine extract:

Berberine extract has been shown to out-perform the leading pharmaceutical product (Metformin; Glucophage) in a double blind placebo test, in controlling blood sugar levels and with NO side effects.  Controlling blood sugar levels prevents the storage of fatty deposits as sugar which is not burnt for energy (too many carbs), is stored as fat.

N-Acetyl- L-Carnitine:

It is a nutrient and supplement.  L-carnitine is made from the amino acids lysine and methionine in the body.  NACL lowers elevated blood levels of Leptin by increasing the absorption and function of Leptin by the Leptin receptors in the fat cells.  L-Carnitine plays a crucial role in the production of energy in the mitochondria in cells.  It transports fatty acids into the mitochondria to be burnt for energy.

XTREME  Weight Loss 3X Capsules (with Sugar, Insulin & Leptin control)

XTREME  Weight Loss 3X Capsules food supplement has been specially formulated to help address the key problem issues of weight gain or difficulty in losing weight, namely:  High Blood Sugar levels, Insulin Resistance and Leptin Resistance. Works best with a healthy low kilojoule (calorie) diet and exercise program (cardiovascular and resistance training).


Take 2 capsules with each meal up to 3 times per day.  Take with 200-300ml water.